Sevgi Özdemir Araştırma Grubu

Name : Sevgi Kılıç Özdemir

Education:

 

B.S          : Hacettepe University, Chemical Engineering

M.S.       : The Pennsylvania State University, Chemical Engineering

PhD        : University of Pittsburgh, Chemical Engineering

 

Experience:

 

  • Post-Doctoral Associate, Cardiovascular Institute at the UPMC Health System (11/03-10/05)
  • Research Assistant, University of Pittsburgh (09/98-10/03)

 

Research Area(s):

 

Design and characterization of microbubbles as ultrasound contrast agents, targeted drug delivery via microbubbles and liposomes, surface active agents, lung surfactants, design and synthesis of functional polymers, polymeric composites, polyurethane foams,

 

 

Courses:

 

CHE 321 Thermodynamics II

CHE 312 Seperation Processes

CHE 411 Chemical Engineering Lab III

CHE 534 Advanced Mass Transfer

Graduate Students:  Melis Gezgin

 

Undergraduate Students:             Ece Namlı

Tuğba Şahin

Ezgi Yıldırım

Safiye Yaldız

 

Projects:

 

  • Drug Delivery via Targeted Microbubbles as Ultrasound Contrast Agent and Their Use in Cancer Treatment via Controlled Local Drug Release, The Scientific and Technological Research Council of Turkey (TUBITAK), proposed to Primary Subjects R&D Funding Program, Dec. 2013 (Principal Investigator)
  • In-Vitro and In-Vivo Characterization of  First National Product of Ultrasound Contrast Agent Microbubbles,  The Scientific and Technological Research Council of Turkey (TUBITAK), Project number: 113M270, 2013-2016 (Principal Investigator)
  • Design and Characterization of Ultrasound Contrast Agents,  The Scientific and Technological Research Council of Turkey (TUBITAK), Project number:109M494, 2009-2012 (Principal Investigator)
  • Nano Calcite Production, The Scientific and Technological Research Council of Turkey (TUBITAK), Project number:110M104, 2010-2013 (Co-Investigator)

Patents:

 

  • Design and Preparation of Targetable Microbubbles as Ultrasound Contrast Agent, TR 2013/04317 (filed)
  • Hallow Nano Calcite Production, Turkish Patent Institute, TR 2013/00370 (filed)

Publication List (peer reviewed):

 

  • Kilic, S, Wang, Y, Johnson, K, Enick, RM, Beckman, EJ; “Influence of tert-amine groups on the solubility of polymers in CO2” Polymer 2009, 50 (11), 2436
  • Villanueva FS, Lu E, Bowry S, Kilic S, Tom E, Wang J, Gretton J, Pacella JJ, Wagner WR: “Myocardial Ischemic Memory Imaging Using Molecular Echocardiography.” Circulation 2007, 115, 345-352
  • Kilic S, Michalik S, Wang Y., Johnson JK., Enick RM, Beckman EJ; “Phase Behavior of Oxygen-Containing Polymers in CO2” Macromolecules 2007, 40, 1332-1341
  • Kilic S, Michalik S, Wang Y., Johnson JK , Enick RM, Beckman EJ; “Effect of Grafted Lewis Base Groups on the Phase Behavior of Model Poly(dimethyl siloxanes) in CO2” Ind. Eng. Chem. Res. 2003, 42, 6415
  • Shen Z, McHugh M. A., Xu J, Belardi J, Kilic S, Mesiano A, Bane S, Karnikas C, Beckman EJ, Enick RM; “CO2-Solubility of Oligomers and Polymers that Contain the Carbonyl Group” Polymer 2003, 44, 1491
  • Burleigh TD, Shi C, Kilic S, Kovacik S, Thompson T, Enick RM; “Self-Assembled Monolayers of Perfluoroalkyl Amideethanethiols, Fluoroalkylthiols and Alkylthiols for the Prevention of Silver Tarnish” Corrosion 2002, 58, 49
  • Huang Z, Shi C, Xu J, Kilic S, Enick RM, Beckman EJ; “Enhancement of the Viscosity of Carbon dioxide using Styrene/fluoroacrylate Copolymers” Macromolecules 2000, 33, 5437
  • Shi C, Huang Z, Kilic S, Xu J, Enick RM, Beckman EJ; “The Gelation of CO2: A sustainable Route to the Creation of Microcellular Materials” Science 1999, 286, 1540

 

 

Conference Publications

 

  • Bowry S, Kilic S, Wang J, Gretton J, Ottoboni S, Wagner WR, Villanueva FS; “A Novel Double-Shelled Microsphere Targeted To Leukocyte Adhesion Molecules Adheres To Inflamed Microcirculation In Vivo J. American College of Cardiology  2006, 47(4), 149A

 

  • Wang J, Kilic S,  Tom E, Lu E, Schellenberger U,  Schreiner GF, Wagner WR, Villanueva FS; “Vascular Endothelial Growth Factor-Conjugated Ultrasound Microbubbles Adhere to Angiogenic Receptors” Circulation 2005 112 (17): U562
  • Lu E, Kilic S, Bowry S, Wang J, Gretton J, Tom E, Wagner WR, Villanueva FS; “Targeted Echocardiographic Imaging of Endothelial Selectins Identifies Ischemic Memory” Circulation 2005, 112 (17): U561

 

  • Kilic S, Lu E, Tom E, Wagner WR, Villanueva FS; “Modifications of Lipid Microbubble Shell Composition Affect Intravascular Kinetics.” J. American College of Cardiology 2005, 45(3) 271A
  • Enick RM, Beckman EJ, Huang Z, Xu J, Kilic S, Shi C; “Improved geologic sequestration using carbon dioxide thickeners” ACS 2000, 220 U398
  • Shi C, Huang Z, Xu J, Kilic S, Beckman EJ, Enick RM; “Direct Thickeners for Carbon dioxide” Soc. Pet. Eng. J. 2000, 59325

 

 

Conference Presentations:

 

  • Colak, F., Adivar, E., Kose, D., Kilic-Ozdemir, S. “Investigation of Protein Adsorption onto PEGylated Surfaces” PPM 2013 International Porous and Powder Materials Symposium and Exhibition, Cesme-Izmir, September 3-6, 2013
  • Sagdic EA, Bolukcu ES, Kose D, Ozdemir E, Kilic-Ozdemir S, “Enhancement of Stability of Microbubbles As Ultrasound Contrast Agents” 244th American Chemical Society National Meeting, Philadelphia, PA, August 19-23, 2012
  • Toprak G, Alici SD, Ulkeryildiz E, Kilic-Ozdemir S, Ozdemir S, “Nano Calcite Production” 244th American Chemical Society National Meeting, Philadelphia, PA, August 19-23, 2012
  • Ozbakir O, Beceren B, Okur S, Ozdemir E, Kilic-Ozdemir S, “Optimization of Poly(ethylene glycol) Density for Preparation of Blood-Compatible Material” 7th Nanoscience and Nanotechnology Conference, Sabancı University, Istanbul,  June 27, 2011
  • Kose D, Binici D, Okur S, Ozdemir E, Kilic-Ozdemir S, “Phase Behavior and Morphology of Phospholipid Langmuir-Blodgett Monolayers” 7th Nanoscience and Nanotechnology Conference, Sabancı University, Istanbul,  June 27, 2011
  • Molva M, Meyva Y, Fidan O, Kilic-Ozdemir S, Ozdemir E  “Production of Calcite from Aggregated Nano Clusters” 7th Nanoscience and Nanotechnology Conference, Sabancı University, Istanbul,  June 27, 2011
  • Akinci SZ, Okur S, Ozdemir E, Kilic-Ozdemir S, “Investigation of Shell Characteristics of Contrast Agents for Ultrasonography” 6th Nanoscience and Nanotechnology Conference, Cesme-Izmir, June 15-18, 2010
  • Akinci SZ, Yoruk S, Sen AE, Ozdemir E, Okur S, Kilic-Ozdemir S,Protein Adsorption on Cholesterol Incorporated Langmuir-Blodgett Phospholipid-Emulsifier Monolayers” 6th Nanoscience and Nanotechnology Conference, Cesme-Izmir, June 15-18, 2010
  • Akinci SZ., Bekat T, Kilic-Ozdemir S, Okur S, “AFM and Kelvin Probe Study of Emulsifier Incorporated Phospholipids” 6th Nanoscience and Nanotechnology Conference, Cesme-Izmir, June 15-18, 2010
  • ·         Tekin UA, Islamoglu R, Kilic-Ozdemir S, Okur S, Ozdemir E, Development of a Humidity Sensor Using PEG40-Stearate” 6th Nanoscience and Nanotechnology Conference, Cesme-Izmir, June 15-18, 2010
  • Akinci SZ, Bekat T, Ozdemir E, Okur S, Kilic-Ozdemir S, “Ultrason Görüntülemede Kullanılan Mikroköpükçüklerin Üretilmesi” 9. Ulusal Kimya Mühendisliği Kongresi, Ankara, June 22-25, 2010                                                               
  • Akinci SZ., Ceylan S., Bergama OE., Ozdemir E., Okur S., Kilic-Ozdemir S., “Towards the Development of Stable Ultrasound Contrast Agents” 5th Nanoscience and Nanotechnology Conference, Anadolu University, Eskisehir, June 8-12, 2009
  • Kilic-Ozdemir S., Okur S., Ozdemir E., “Humidity Sensing Properties of PEG-40 LB films detected using QCM technique” 5th Nanoscience and Nanotechnology Conference, Anadolu University, Eskisehir, June 8-12, 2009
  • Tom E, Kilic S, Wagner WR, Villanueva FS; “Design of CD62P-Targeted Ultrasound Contrast Agents Using Mathematical Modeling” Biomedical Engineering Society Annual Meeting (BMES) 2006, October 11-14, Chicago, IL
  • Bowry S, Kilic S, Wang J, Gretton J, Ottoboni S, Wagner WR, Villanueva FS; “A Novel Double-Shelled Microsphere Targeted To Leukocyte Adhesion Molecules Adheres To Inflamed Microcirculation In Vivo” 55th Annual Scientific Session of the American-College-of Cardiology, Atlanta, GA, March 11-14, 2006
  • Wang J, Kilic S,  Tom E, Lu E, Schellenberger U,  Schreiner GF, Wagner WR, Villanueva FS; “Vascular Endothelial Growth Factor-Conjugated Ultrasound Microbubbles Adhere to Angiogenic Receptors” 78th Annual Scientific Session of the American-Heart-Association, Dallas, TX, Nov. 13-16, 2005
  • Lu E, Kilic S, Bowry S, Wang J, Gretton J, Tom E, Wagner WR, Villanueva FS; “Targeted Echocardiographic Imaging of Endothelial Selectins Identifies Ischemic Memory” 78th Annual Scientific Session of the American-Heart-Association, Dallas, TX, Nov. 13-16, 2005
  • Kilic S, Lu E, Tom E, Wagner WR, Villanueva FS; “Modifications of Lipid Microbubble Shell Composition Affect Intravascular Kinetics” 54th Annual Scientific Session of the American-College-of-Cardiology, Orlando, FL , March 6, 2005
  • Kilic S, Michalik S, Enick RM, Beckman EJ; “Effect of Molecular Structure on Phase Behavior of Polymers in CO2” AIChE Annual Meeting, Polymerization and Polymer Processing with Supercritical Fluids I, San Francisco, CA, Nov. 16-21, 2003
  • Wang Y, Kilic S, Michalik S, Enick RM, Beckman EJ, Johnson, K; “Molecular Modeling Design and Optimization of Non-fluorous CO2-philic Polymers” AIChE Annual Meeting, Thermodynamic and Transport Properties of Supercritical Fluids, San Francisco, CA, Nov. 16-21, 2003
  • Kilic S, Michalik S, Enick RM, Beckman EJ; “Engineering of Non- fluorous CO2-Philic Polymers Containing Lewis Bases” AIChE Annual Meeting, Thermodynamics and Transport Properties in Compressed and Supercritical Fluids, Indianapolis, IN, Nov. 3-8, 2002
  • Kilic S, Enick RM, Beckman EJ; “The Effect of Spacer Length and Number of Aromatic Rings in the Copolymer of Aromatic Acrylate-Fluoroacrylate on CO2 solubility and Viscosity Enhancement” AIChE  Annual Meeting, Thermodynamics and Transport Properties of Supercritical Fluids, Reno, Nevada, Nov. 4-9, 2001
  • Enick RM, Beckman EJ, Huang Z, Xu J, Kilic S, Shi C; “Improved geologic sequestration using carbon dioxide thickeners” 219th American Chemical Society National Meeting San Francisco, CA, March 26-30, 2000
  • Kilic S, Enick RM, Beckman EJ; “Carbon Dioxide Viscosity Enhancement Ability of Acrylate Copolymers Possessing Flexible Spacer and Aromatic Units” AIChE Annual Meeting, Transport & Thermodynamic Properties, Nov. 12-17, 2000 Los Angeles, CA.
  • Kilic S, Matsoukas T; “Dynamics of Silica Gels by Dynamic Light Scattering” 72nd ACS Colloid and Surface Science Symposium, June 21-24, 1998 University Park, PA.
  • Kilic S, Matsoukas T; “Light Scattering from Inorganic Polymers” AIChE  Annual Meeting, Los Angeles, CA, Nov. 16-21, 1997